@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAXh3NgRrIf5SPaaQNyZNgiShXh8jhsO-RSmU8AUUQeJ4
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAXh3NgRrIf5SPaaQNyZNgiShXh8jhsO-RSmU8AUUQeJ4#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix scomp: <
http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/
> .
@prefix ProteinComplex: <
http://amigo.geneontology.org/amigo/term/GO:0043234
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix proteinModification: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
> .
@prefix psimod: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:
> .
@prefix obo: <
http://purl.obolibrary.org/obo/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
scomp:p85%2Fp110%20PI3Kinase%20Complex
a
ProteinComplex:
.
sub:_1
hasAgent:
scomp:p85%2Fp110%20PI3Kinase%20Complex
;
a
go:0016301
.
sub:_2
belv:variantOf
hgnc:391
;
a
proteinModification:
,
psimod:00696
.
sub:_3
occursIn:
obo:CL_0000233
,
species:9606
;
rdf:object
sub:_2
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> p(HGNC:AKT1,pmod(P,S,473))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_5
;
pav:version
"20131211" .
sub:_4
prov:value
"Akt activation is dependent on its phosphorylation at Thr308 and Ser473. The mechanism by which thrombin induces Akt phosphorylation is controversial, as is the role of Akt in platelet function.Platelet PAR stimulation causes rapid Akt phosphorylation downstream of PLC; while in the continuous stimulation, ADP and PI3K are required for maintaining Akt phosphorylation. " ;
prov:wasQuotedFrom
pubmed:17883592
.
sub:_5
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:17883592
;
prov:wasDerivedFrom
beldoc:
,
sub:_4
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:33:12.506+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}