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[In contrast to our original hypothesis, no defect of the anti-inflammatory potential of TGF? and IL10 was observed in children with IBD or EO-IBD except two infants who presented with granuloma-positive colitis at 3 months of life: no response to IL10 was observed secondary to mutations in the ? (p.R262C) or ? (p.E141X) chain of IL10R, respectively, although a fully functional Jak-STAT3 pathway was present in both patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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Gene-disease associations inferred from text-mining the literature.
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