@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_head {
  this: np:hasAssertion dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_assertion;
    np:hasProvenance dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_provenance;
    np:hasPublicationInfo dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_assertion a np:Assertion .
  
  dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_provenance a np:Provenance .
  
  dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_assertion {
  miriam-gene:3949 a ncit:C16612 .
  
  lld:C0020445 a ncit:C7057 .
  
  dgn-gda:DGNa0185c418901ef3d98ab34362a61b7c8 sio:SIO_000628 miriam-gene:3949, lld:C0020445;
    a sio:SIO_001122 .
}

dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_provenance {
  dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_assertion dcterms:description
      "[1130 unrelated subjects with molecularly defined FH were screened for mutation R46L in the PCSK9 gene and cell culture experiments were performed to study the effect of high concentrations of low density lipoprotein (LDL) on the binding of PCSK9 to the LDL receptor (LDLR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:19917273;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP776115.RAXfYCgJCSGXURtftVg9ddjfmHcLVv4W2jE7lU4uMYYKc130_publicationInfo {
  this: dcterms:created "2016-05-13T12:47:37+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}