http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#Head http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#provenance http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#pubinfo http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=2674 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://disease-ontology.org/term/DOID:1936 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000891 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0000947 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_1 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/Low%20Density%20Lipoprotein http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:"Low Density Lipoprotein") -> p(HGNC:DAPK1) http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_3 http://www.w3.org/ns/prov#value Western blots showed that SMCs did not express DAP kinase protein when cultured in the absence of agLDL. In contrast, strong upregulation of DAP kinase protein could be detected after 2 days of agLDL treatment (Figure 3A). DAP kinase expression was associated with enhanced levels of the tumor suppressor protein p53. We also observed a progressive increase in Bax and TNF receptor 2 expression during foam cell formation. Furthermore, it was demonstrated that agLDL could significantly induce (3-fold) both DAP kinase and Bax gene transcription (Figure 3B). http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12482829 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12482829 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#_3 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#pubinfo http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://purl.org/dc/terms/created 2014-07-03T14:31:57.293+02:00 http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234