@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAXZ--g7eUYNZLPs_j9wrWeJfa9gvQxmQOebc1SJvo_Hg#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix schem: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix do: <http://disease-ontology.org/term/DOID:> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: hgnc:2674;
    a Protein: .
  
  sub:_2 occursIn: do:1936, obo:CL_0000891, obo:UBERON_0000947, species:9606;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject schem:Low%20Density%20Lipoprotein;
    a rdf:Statement .
  
  sub:assertion rdfs:label "a(SCHEM:\"Low Density Lipoprotein\") -> p(HGNC:DAPK1)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_4;
    pav:version "20131211" .
  
  sub:_3 prov:value "Western blots showed that SMCs did not express DAP kinase protein when cultured in the absence of agLDL. In contrast, strong upregulation of DAP kinase protein could be detected after 2 days of agLDL treatment (Figure 3A). DAP kinase expression was associated with enhanced levels of the tumor suppressor protein p53. We also observed a progressive increase in Bax and TNF receptor 2 expression during foam cell formation. Furthermore, it was demonstrated that agLDL could significantly induce (3-fold) both DAP kinase and Bax gene transcription (Figure 3B).";
    prov:wasQuotedFrom pubmed:12482829 .
  
  sub:_4 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:12482829;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:31:57.293+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}