sub:assertion { d:DB05476v:identifier "DB05476" ; v:namespace "drugbank" ; v:uri "http://bio2rdf.org/drugbank:DB05476" ; v:x-identifiers.org <http://identifiers.org/drugbank/DB05476> ; dv:drugbank-id "DB05476" ; dv:x-cas <http://bio2rdf.org/cas:> ; dct:description "WX-UK1 is a 3-amidinophenylalanine-based non-cytotoxic small molecule that belongs to a new class of drugs. In animal models, WX-UK1 blocks tumor cell invasion, metastasis and primary tumor growth by inhibiting serine proteases and the urokinase Plasminogen Activator (uPA) system, which have been shown to play a key role in metastasis and primary tumor growth of breast, gastric, colon cancer, and various other solid tumors. Independent studies show that administration of Wx-UK1 resulted in a decrease of tumor cell invasion, suggesting its efficacy as a an adjuvant antimetastatic therapy of carcinomas."@en ; dct:identifier "drugbank:DB05476" ; dct:title "WX-UK1"@en ; adv:Drug ; rdfs:label "WX-UK1 [drugbank:DB05476]"@en ; rdfs:seeAlso <http://www.drugbank.ca/drugs/DB05476> . }