. . . . . . . . . . . . . . . . . . . . . . . "kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> (p(HGNC:IGF1) -| tscript(p(HGNC:ESR1)))" . "p(HGNC:IGF1) -| tscript(p(HGNC:ESR1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "IGF-I decreased ERalpha activity in the presence of estradiol, and this effect was mediated by PI3K. We also observed a regulated interaction between beta-catenin, one of the main GSK3 nuclear targets, and ERalpha. Transfection with a nondegradable mutant of beta-catenin blocked the increase in ERalpha transcriptional activity induced by the PI3K inhibitor wortmannin, suggesting a role for beta-catenin in estrogen signaling. " . . "Selventa" . . . . "2014-07-03T14:32:56.511+02:00"^^ . . .