http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#Head http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#provenance http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_1 http://purl.obolibrary.org/obo/RO_0002204 http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=2448 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0001134 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_1 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://amigo.geneontology.org/amigo/term/GO:0014889 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.w3.org/2000/01/rdf-schema#label bp(GOBP:"muscle atrophy") -> r(RGD:Ctsl1) http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_3 http://www.w3.org/ns/prov#value Among the strongly induced genes were many involved in protein degradation, including polyubiquitins, Ub fusion proteins, the Ub ligases atrogin-1/MAFbx and MuRF-1, multiple but not all subunits of the 20S proteasome and its 19S regulator, and cathepsin L. Many genes required for ATP production and late steps in glycolysis were down-regulated, as were many transcripts for extracellular matrix proteins. Some genes not previously implicated in muscle atrophy were dramatically up-regulated (lipin, metallothionein, AMP deaminase, RNA helicase-related protein, TG interacting factor) and several growth-related mRNAs were down-regulated (P311, JUN, IGF-1-BP5) http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/14718385 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/14718385 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#_3 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://purl.org/dc/terms/created 2014-07-03T14:32:14.736+02:00 http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAVyZMrepnXM4PTuk7RzBtvDGV-BYcdMKRlST3zqjcxtE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234