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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#_4 http://www.w3.org/ns/prov#value When P6 cerebellar glia transfected with plasmids encoding the erbB2-Luciferase reporter, measured level of luciferase activity in glia alone or in glia after the addition of neurons indicated that neuronal contact induced a 2-fold increase in erbB2 promoter activity. The erbB2 promoter activity was completely abolished by cotranfection with dominant-negative Notch1 (OCDN1). Constitutively active Notch1 (FCDN1) expression induced a 1.75 +/- 0.23-fold ( p < 0.007) increase of erbB2 protein in glia. These results suggest that Notch1 upregulated erbB2 expression. http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12853432 http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12853432 http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#_4 http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c#pubinfo http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c http://purl.org/dc/terms/created 2014-07-03T14:32:04.570+02:00 http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAVaE5vonci2B2CKNV0WX-fngHCEm-6VCPdC6EysKN05c http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234