@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix rgd: . @prefix geneProductOf: . @prefix RNA: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: rgd:3187; a Protein: . sub:_2 geneProductOf: rgd:2561; a RNA: . sub:_3 occursIn: obo:CL_0000125, species:10116; rdf:object sub:_2; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(RGD:Notch1) -> r(RGD:Erbb2)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_5; pav:version "20131211" . sub:_4 prov:value "When P6 cerebellar glia transfected with plasmids encoding the erbB2-Luciferase reporter, measured level of luciferase activity in glia alone or in glia after the addition of neurons indicated that neuronal contact induced a 2-fold increase in erbB2 promoter activity. The erbB2 promoter activity was completely abolished by cotranfection with dominant-negative Notch1 (OCDN1). Constitutively active Notch1 (FCDN1) expression induced a 1.75 +/- 0.23-fold ( p < 0.007) increase of erbB2 protein in glia. These results suggest that Notch1 upregulated erbB2 expression."; prov:wasQuotedFrom pubmed:12853432 . sub:_5 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:12853432; prov:wasDerivedFrom beldoc:, sub:_4 . } sub:pubinfo { this: dct:created "2014-07-03T14:32:04.570+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }