@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAVZPJnu0Yr5sPAV8b2r7pXw7uJkZ1MRHFJqCGFocTDN0> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAVZPJnu0Yr5sPAV8b2r7pXw7uJkZ1MRHFJqCGFocTDN0#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix rgd: <http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: rgd:69051;
    a Protein: .
  
  sub:_2 hasAgent: sub:_3;
    a go:0016301 .
  
  sub:_3 geneProductOf: rgd:1309438;
    a Protein: .
  
  sub:_4 occursIn: obo:CL_0000746, obo:UBERON_0000948, species:10116;
    rdf:object sub:_2;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "p(RGD:Tgfb1) -> kin(p(RGD:Map3k7))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_6;
    pav:version "20131211" .
  
  sub:_5 prov:value "In parallel with the upregulation of TGF-{beta}1, the protein levels of TAK1 were significantly increased 1.66 ± 0.14-, 1.97 ± 0.16-, and 1.57 ± 0.07-fold (P < 0.01) at 1, 3, and 7 days post-MI compared with sham-operated rats (Fig. 2, A and B). Although there was no change in the protein levels of MKK3/6 and p38 MAPK levels throughout the time course, P-MKK3/6 and P-p38 MAPK were increased significantly (P-MKK3/6: 2.20 ± 0.19-, 2.55 ± 0.47-, and 3.29 ± 0.32-fold; P-p38 MAPK: 1.90 ± 0.03-, 2.03 ± 0.06-, and 2.35 ± 0.06-fold at 1, 3, and 7 days after MI), indicating the activation of the TGF-{beta}1-TAK1-MKK3/6-p38 MAPK pathway.";
    prov:wasQuotedFrom pubmed:16183734 .
  
  sub:_6 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:16183734;
    prov:wasDerivedFrom beldoc:, sub:_5 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:32:50.612+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}