. . . . . . . . . . . . . . . . . . . "kin(p(SFAM:\"AKT Family\")) =| kin(p(HGNC:GSK3B))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "PI3K-Akt-GSK3b pathway Glycogen-synthase kinase 3b (GSK3b) is a distinct substrate of Akt1 that has been shown to modulate hypertrophy. GSK3b activity is inhibited by Akt1 phosphorylation [65] (Fig. 1). Expression of a dominantnegative, kinase-inactive form of GSK3b induces dramatic hypertrophy in skeletal myotubes [6]. In cardiac hypertrophy, GSK3b phosphorylation is also evident [66], and expression of a dominant-negative form of GSK3b can induce cardiac hypertrophy [66]." . . "Selventa" . . . . "2014-07-03T14:32:07.486+02:00"^^ . . .