. . . . . . . "[Here, we identified an A? variant phosphorylated at Ser26 residue (pSer26A?) in transgenic mouse models of AD and in human brain that shows contrasting spatio-temporal distribution as compared to non-phosphorylated A? (npA?) or other modified A? species. pSer26A? is particularly abundant in intraneuronal deposits at very early stages of AD, but much less in extracellular plaques. pSer26A? assembles into a specific oligomeric form that does not proceed further into larger fibrillar aggregates, and accumulates in characteristic intracellular compartments of granulovacuolar degeneration together with TDP-43 and phosphorylated tau.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:18:14+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .