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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAV4537jDW-eexZP7gBgTGE9gYNwBF8uuSPanbIsCLzO4#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAV4537jDW-eexZP7gBgTGE9gYNwBF8uuSPanbIsCLzO4#_4 http://www.w3.org/ns/prov#value (from text) We confirmed this essential role for huntingtin on our arrays, detecting the general down-regulation of genes involved in growth, proliferation and cellular differentiation (Fig. 6). A subset of these transcripts appear to function specifically within the brain: Serpinf1, Emp3, Tcfap2c, Dlx3 and Elavl4. Many general growth-related or mitogenic mRNAs (Ghrh, Scgb3a1, Cdkn1c, Sp6, Gkn1, Igf2) also exhibited reduced expression. 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