sub:assertion {
d:DB00440 dv:ddi-interactor-in dr:DB00440_DB01026 .
d:DB01026 dv:ddi-interactor-in dr:DB00440_DB01026 .
dr:DB00440_DB01026 dct:identifier "drugbank_resource:DB00440_DB01026" ;
dct:title "DDI between Trimethoprim and Ketoconazole - The strong CYP2C9 inhibitor, Ketoconazole, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Ketoconazole is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Trimethoprim and Ketoconazole - The strong CYP2C9 inhibitor, Ketoconazole, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Ketoconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00440_DB01026]"@en .
}