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[We have previously shown that the downregulation of Orai1 protein representing the major molecular component of endogenous SOCE in human prostate cancer cells, and constituting the principal source of Ca(2+) influx used by the cell to trigger apoptosis, contributes to the establishment of an apoptosis-resistant phenotype (Cell Death Dis.2010 Sep 16;1:e75.).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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