sub:assertion { d:DB01030dv:ddi-interactor-indr:DB01030_DB01136 . d:DB01136dv:ddi-interactor-indr:DB01030_DB01136 . dr:DB01030_DB01136dct:identifier "drugbank_resource:DB01030_DB01136" ; dct:title "DDI between Topotecan and Carvedilol - The p-glycoprotein inhibitor, Carvedilol, may increase the bioavailability of oral Topotecan. A clinically significant effect is also expected with IV Topotecan. Concomitant therapy should be avoided."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Topotecan and Carvedilol - The p-glycoprotein inhibitor, Carvedilol, may increase the bioavailability of oral Topotecan. A clinically significant effect is also expected with IV Topotecan. Concomitant therapy should be avoided. [drugbank_resource:DB01030_DB01136]"@en . }