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http://semanticscience.org/resource/SIO_000139
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kin(p(RGD:Prkg2)) -| a(SCHEM:Calcium)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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Cardiovascular Physiology Concepts
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Cardiovascular Physiology Concepts
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When NO is formed by an endothelial cell, for example, it readily diffuses out of the cell and into adjacent smooth muscle cells where is binds to a heme moiety on guanylyl cyclase and activates this enzyme to produce cGMP from GTP. Increased cGMP activates a kinase that subsequently leads to the inhibition of calcium influx into the smooth muscle cell, and decreased calcium-calmodulin stimulation of myosin light chain kinase (MLCK).
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Selventa
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2014-07-03T14:31:29.080+02:00
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