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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RASUaQ5_G5r-Gnbt3rYuvPq0Cp9FVyQyjCmOeW--2RmJw#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RASUaQ5_G5r-Gnbt3rYuvPq0Cp9FVyQyjCmOeW--2RmJw#_6 http://www.w3.org/ns/prov#value We demonstrate that p90rsk-1, p90rsk-2, gsk-3, ERK-2, and p70S6K kinases are components of the protein translation complex. gsk-3b is a constitutively active kinase and phosphorylation by p90rsk inhibits its kinase activity (47). One of the known gsk-3 substrates is the translation initiation factor eIF2B. Phosphorylation of this translation initiation factor decreases translation (49, 50). 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