sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "20131211" . sub:_4prov:value "We flanked the entire coding region of Shox2 with LoxP sites (10), such as to induce deletion upon exposure to the Cre recombinase (Fig. 1). Mice carrying such a floxed allele as well as a fully deleted copy and the limb-specific Prx1-Cre transgene (11) (hereafter referred to as Shox2 c/?) were thus devoid of any Shox2 transcript in their developing limbs (Fig. 1 b and c). We looked at Runx2 (mRNA) expression in Shox2 c/- mice, and, strikingly, very few Runx2-positive cells were scored in the humerus at E12.5 (Fig. 5 a)." ; prov:wasQuotedFrompubmed:16537395 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:16537395 ; prov:wasDerivedFrombeldoc: , sub:_4 . }