[ {
  "@graph" : [ {
    "@id" : "http://identifiers.org/ncbigene/3818",
    "@type" : [ "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612" ]
  }, {
    "@id" : "http://linkedlifedata.com/resource/umls/id/C0019243",
    "@type" : [ "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057" ]
  }, {
    "@id" : "http://rdf.disgenet.org/gene-disease-association.ttl#DGN4812509575618e328af1891d67db0e00",
    "@type" : [ "http://semanticscience.org/resource/SIO_001121" ],
    "http://semanticscience.org/resource/SIO_000628" : [ {
      "@id" : "http://identifiers.org/ncbigene/3818"
    }, {
      "@id" : "http://linkedlifedata.com/resource/umls/id/C0019243"
    } ]
  } ],
  "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_assertion"
}, {
  "@graph" : [ {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_publicationInfo"
    } ]
  }, {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_assertion",
    "@type" : [ "http://www.nanopub.org/nschema#Assertion" ]
  }, {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_provenance",
    "@type" : [ "http://www.nanopub.org/nschema#Provenance" ]
  }, {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_publicationInfo",
    "@type" : [ "http://www.nanopub.org/nschema#PublicationInfo" ]
  } ],
  "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_head"
}, {
  "@graph" : [ {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_assertion",
    "http://purl.org/dc/terms/description" : [ {
      "@language" : "en",
      "@value" : "[Although previous data suggested that symptoms in HAE might be mediated via complement system activation, a combination of recent clinical data, in vitro studies, and analysis of C1INH-deficient mice all indicate that the major mediator of angioedema is bradykinin: (1) a vascular permeability enhancing factor can be generated in vitro in C1INH-depleted, C2-deficient plasma, but not from C1INH-depleted, contact system-deficient plasma; this factor was identified by sequence analysis as bradykinin; (2) bradykinin can be detected in the plasma of HAE patients during attacks of angioedema; (3) in several members of one family, expression of a C1INH variant that inhibits contact system proteases but has defective inhibition of C1r and C1s does not result in HAE; (4) C1INH-deficient (C1INH-/-) mice have a defect in vascular permeability that is suppressed by treatment with specific plasma kallikrein inhibitors and by bradykinin type 2 receptor (Bk2R) antagonists, and is eliminated in C1INH-/-, Bk2R-/- double-deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."
    } ],
    "http://purl.org/ontology/wi/core#evidence" : [ {
      "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature"
    } ],
    "http://semanticscience.org/resource/SIO_000772" : [ {
      "@id" : "http://identifiers.org/pubmed/15596403"
    } ],
    "http://www.w3.org/ns/prov#wasDerivedFrom" : [ {
      "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225"
    } ],
    "http://www.w3.org/ns/prov#wasGeneratedBy" : [ {
      "@id" : "http://purl.obolibrary.org/obo/eco.owl#ECO_0000203"
    } ]
  }, {
    "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225",
    "http://purl.org/pav/2.0/importedOn" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#date",
      "@value" : "2014-02-25"
    } ]
  }, {
    "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature",
    "@type" : [ "http://purl.obolibrary.org/obo/eco.owl#ECO_0000212" ],
    "http://www.w3.org/2000/01/rdf-schema#comment" : [ {
      "@language" : "en",
      "@value" : "Gene-disease associations inferred from text-mining the literature."
    } ],
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@language" : "en",
      "@value" : "DisGeNET evidence - LITERATURE"
    } ]
  } ],
  "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_provenance"
}, {
  "@graph" : [ {
    "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2014-10-02T12:40:25+02:00"
    } ],
    "http://purl.org/dc/terms/rights" : [ {
      "@id" : "http://opendatacommons.org/licenses/odbl/1.0/"
    } ],
    "http://purl.org/dc/terms/rightsHolder" : [ {
      "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#IBIGroup"
    } ],
    "http://purl.org/dc/terms/subject" : [ {
      "@id" : "http://semanticscience.org/resource/SIO_000983"
    } ],
    "http://purl.org/net/provenance/ns#usedData" : [ {
      "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf"
    } ],
    "http://purl.org/pav/2.0/authoredBy" : [ {
      "@id" : "http://orcid.org/0000-0001-5999-6269"
    }, {
      "@id" : "http://orcid.org/0000-0002-7534-7661"
    }, {
      "@id" : "http://orcid.org/0000-0002-9383-528X"
    }, {
      "@id" : "http://orcid.org/0000-0003-0169-8159"
    }, {
      "@id" : "http://orcid.org/0000-0003-1244-7654"
    } ],
    "http://purl.org/pav/2.0/createdBy" : [ {
      "@id" : "http://orcid.org/0000-0003-0169-8159"
    } ],
    "http://purl.org/pav/2.0/version" : [ {
      "@value" : "v2.1.0.0"
    } ]
  }, {
    "@id" : "http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf",
    "http://purl.org/pav/2.0/version" : [ {
      "@value" : "v2.1.0"
    } ]
  } ],
  "@id" : "http://rdf.disgenet.org/nanopublications.trig#NP825818.RASAOpkRBtgqNdHm1MYZG0499k6CbsNCadrC9UvBrtmkY130_publicationInfo"
} ]