sub:assertion { d:DB00186dv:ddi-interactor-indr:DB00186_DB00313 . d:DB00313dv:ddi-interactor-indr:DB00186_DB00313 . dr:DB00186_DB00313dct:identifier "drugbank_resource:DB00186_DB00313" ; dct:title "DDI between Lorazepam and Valproic Acid - Valproic acid may increase the serum concentration of Lorazepam by reducing Lorazepam metabolism. The Lorazepam dose should be reduced by 50% during concomitant therapy. Monitor for increased Lorazepam effects and toxicity."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Lorazepam and Valproic Acid - Valproic acid may increase the serum concentration of Lorazepam by reducing Lorazepam metabolism. The Lorazepam dose should be reduced by 50% during concomitant therapy. Monitor for increased Lorazepam effects and toxicity. [drugbank_resource:DB00186_DB00313]"@en . }