. . . . . . . . . . . . . "a(CHEBI:glucocorticoid) -> r(HGNC:TRIM63)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Expression of MuRF1 and MAFbx is stimulated when the nerve innervating a muscle is cut, thus resulting in paralysis and severe atrophy; these genes are also upregulated by simple immobilization of the muscle, or by treatment with a glucocorticoid, which causes muscle cachexia [11]. More recently, a predictive experiment was performed, in which sepsis-induced atrophy was induced to determine whether this distinct model of atrophy might also increase expression of MuRF1 and MAFbx. Both of these genes were upregulated several-fold during sepsis [72], and this upregulation could be blocked by a pharmacologic inhibitor of glucocorticoids [72]." . . "Selventa" . . . . "2014-07-03T14:32:07.415+02:00"^^ . . .