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The interaction may be beneficial when the anticholinergic action is a side effect. Monitor for decreased efficacy of both agents. http://bio2rdf.org/drugbank_resource:DB00382_DB00405 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug-Drug-Interaction http://bio2rdf.org/drugbank_resource:DB00382_DB00405 http://www.w3.org/2000/01/rdf-schema#label DDI between Tacrine and Dexbrompheniramine - The therapeutic effects of the central acetylcholinesterase inhibitor, Tacrine, and/or the anticholinergic, Dexbrompheniramine, may be reduced due to antagonism. The interaction may be beneficial when the anticholinergic action is a side effect. Monitor for decreased efficacy of both agents. 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