@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_head {
  this: np:hasAssertion dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_assertion;
    np:hasProvenance dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_provenance;
    np:hasPublicationInfo dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_assertion a np:Assertion .
  
  dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_provenance a np:Provenance .
  
  dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_assertion {
  miriam-gene:925 a ncit:C16612 .
  
  lld:C2921627 a ncit:C7057 .
  
  dgn-gda:DGN64eda4141b05c6879879dca89a43cfa3 sio:SIO_000628 miriam-gene:925, lld:C2921627;
    a sio:SIO_001121 .
}

dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_provenance {
  dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_assertion dcterms:description
      "[We previously reported that low expression of the antiproliferative gene TOB1 in CD4⁺ T cells of individuals presenting with an initial central nervous system (CNS) demyelinating event (a clinically isolated syndrome), correlated with high risk for progression to MS. We report that experimental autoimmune encephalomyelitis (EAE) in Tob1⁻/ ⁻ mice was associated with augmented CNS inflammation, increased infiltrating CD4⁺ and CD8⁺ T cell counts, and increased myelin-reactive Th1 and Th17 cells, with reduced numbers of regulatory T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:23797093;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP194533.RARH5YBgzhlDtQI8nT1RsOZ7fucHd8HGgedfhMan14ohM130_publicationInfo {
  this: dcterms:created "2014-10-02T12:33:47+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}