. . . . . . . . . . . . . . . "cat(p(RGD:Pde1b)) =| a(SCHEM:\"Cyclic GMP\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." . . "Selventa" . . . . "2014-07-03T14:32:06.860+02:00"^^ . . .