sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "20131211" .
  sub:_4 prov:value "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." ;
    prov:wasQuotedFrom pubmed:12920188 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12920188 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}