sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "20131211" .
  sub:_5 prov:value "PU.1 and Spi-B directly regulate the expression of several genes associated with BCR signaling such as BLNK, B220, Btk, P2Y10, and Grap2 [10, 29–32].Spi-C has DNA-binding specificity identical to PU.1 and Spi-B and therefore might regulate many of the same genes as these transcription factors [25].The levels of BLNK, Lyn, B220, Btk, and P2Y10 transcripts were significantly decreased in bone marrow pre-B and immature B cells enriched from Spi-C transgenic mice compared with the wild type. In contrast, Grap2 was increased in transgenic Spi-C pre-B cells compared with wild type (Real time RT-PCR analysis, n = 3)" ;
    prov:wasQuotedFrom pubmed:18792411 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:18792411 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}