Nanopublications

@prefix this: <http://bio2rdf.org/drugbank:DB00612_nanopub.RAQpA4pLobtWCI7nlmufKyuQRLROPQJ7M7jcUTJutfT5I> .
@prefix sub: <http://bio2rdf.org/drugbank:DB00612_nanopub.RAQpA4pLobtWCI7nlmufKyuQRLROPQJ7M7jcUTJutfT5I#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:publicationInfo ;
    a np:Nanopublication .
}

sub:assertion {
 d:DB00612 v:identifier "DB00612" ;
 v:namespace "drugbank" ;
 v:uri "http://bio2rdf.org/drugbank:DB00612" ;
 v:x-identifiers.org <http://identifiers.org/drugbank/DB00612> ;
 dv:drugbank-id "APRD00257" , "DB00612" ;
 dv:x-ahfs <http://bio2rdf.org/ahfs:24:24.00> ;
 dv:x-atc <http://bio2rdf.org/atc:C07AB07> ;
 dv:x-bindingdb <http://bio2rdf.org/bindingdb:25751> ;
 dv:x-cas <http://bio2rdf.org/cas:66722-44-9> ;
 dv:x-chebi <http://bio2rdf.org/chebi:3127> ;
 dv:x-chemspider <http://bio2rdf.org/chemspider:2312> ;
 dv:x-dpd <http://bio2rdf.org/dpd:2247439> ;
 dv:x-kegg <http://bio2rdf.org/kegg:C06852> , <http://bio2rdf.org/kegg:D02342> ;
 dv:x-ndc <http://bio2rdf.org/ndc:0378-0523-93> ;
 dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA448641> ;
 dv:x-pubchemcompound <http://bio2rdf.org/pubchem.compound:2405> ;
 dv:x-pubchemsubstance <http://bio2rdf.org/pubchem.substance:46508844> ;
 dv:x-wikipedia <http://bio2rdf.org/wikipedia:Bisoprolol> ;
 dct:description "Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only l-bisoprolol exhibits significant β-blocking activity."@en ;
 dct:identifier "drugbank:DB00612" ;
 dct:title "Bisoprolol"@en ;
 a dv:Drug ;
 rdfs:label "Bisoprolol [drugbank:DB00612]"@en ;
 rdfs:seeAlso <http://www.drugbank.ca/drugs/DB00612> , <http://www.drugs.com/bisoprolol.html> , <http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zeb1667.shtml> , <http://www.rxlist.com/cgi/generic3/bisoprolol.htm> .
}

sub:provenance {
 sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
 dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
 <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime ;
 prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
 <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime ;
 prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
 <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo <http://drugbank.ca> .
}

sub:publicationInfo {
 sub:signature.MCwCFCMgG0xUhccV npx:hasPublicKey "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" ;
 npx:hasSignature "MCwCFCMgG0xUhccVvKUJIfcTPVHYXUt8AhQxNzo+iVGJ3OyEIvLPlRH/r0NVNw==" ;
 npx:signedBy instance: .
 this: dct:created "2018-03-30T11:11:14.373+02:00"^^xsd:dateTime ;
 dct:license <https://creativecommons.org/licenses/by-nc/4.0/> ;
 npx:hasSignatureElement sub:signature.MCwCFCMgG0xUhccV ;
 prov:wasGeneratedBy process: .
 instance: prov:specializationOf codebase: ;
 prov:wasAttributedTo orcid:0000-0002-1267-0234 .
 process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475" ;
 prov:used version: ;
 prov:wasAssociatedWith instance: ;
 prov:wasStartedBy orcid:0000-0002-1267-0234 .
 version: dct:isVersionOf codebase: ;
 pav:version "eda7951a5f6c622c5d2132f50c3093138484a349" ;
 prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}