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[Thus, two major paradoxes in cardiovascular medicine today are: 1) despite the overwhelming evidence that platelet reactivity strongly influences the development of potentially catastrophic events including myocardial infarction and stent thrombosis in the PCI patient, no measurement is made in clinical practice to assess the presence of blood vulnerability (platelet reactivity) and 2) despite the overwhelming evidence that the effect of dual antiplatelet therapy with aspirin and P2Y12 receptor blockers is variable, the guidelines largely recommend a uniform, `one size fits all` dosing of these agents in the PCI patient without any confirmation of an adequate antiplatelet effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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