sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_4 ; pav:version "20131211" . sub:_3prov:value "These results were confirmed by immunoblot analysis of phosphorylated S6 and 4E-binding protein 1 in hepatic lysates (Fig. 3C). Phosphorylation of S6 was inhibited by either regimen of rapamycin administration 4 h after the last dose on day 5, but recovery was different. S6 phosphorylation recovered less with the qod schedule. Interestingly, phosphorylation of 4E-binding protein 1 did not recover during the washout period with either regimen. The basis for these differences in the recovery of phosphorylation of S6 and 4E-binding protein 1 is unclear, but it suggests that S6 phosphorylation might more accurately reflect rapamycin levels than phosphorylation of 4E-binding protein 1" ; prov:wasQuotedFrompubmed:17404113 . sub:_4rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:17404113 ; prov:wasDerivedFrombeldoc: , sub:_3 . }