@prefix this: <http://bio2rdf.org/drugbank:DB01023_nanopub.RAQjRBfNfipGhh1hLOrHvqr2YOtfXJM8xZ8cRYl1cvyNw> .
@prefix sub: <http://bio2rdf.org/drugbank:DB01023_nanopub.RAQjRBfNfipGhh1hLOrHvqr2YOtfXJM8xZ8cRYl1cvyNw#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:publicationInfo ;
    a np:Nanopublication .
}
sub:assertion {
   d:DB01023 v:identifier "DB01023" ;
    v:namespace "drugbank" ;
    v:uri "http://bio2rdf.org/drugbank:DB01023" ;
    v:x-identifiers.org <http://identifiers.org/drugbank/DB01023> ;
    dv:drugbank-id "APRD00374" , "DB01023" ;
    dv:x-ahfs <http://bio2rdf.org/ahfs:24:28.08> ;
    dv:x-atc <http://bio2rdf.org/atc:C08CA02> ;
    dv:x-bindingdb <http://bio2rdf.org/bindingdb:50017710> ;
    dv:x-cas <http://bio2rdf.org/cas:72509-76-3> ;
    dv:x-chebi <http://bio2rdf.org/chebi:585948> ;
    dv:x-chemspider <http://bio2rdf.org/chemspider:3216> ;
    dv:x-dpd <http://bio2rdf.org/dpd:2222000> ;
    dv:x-gtp <http://bio2rdf.org/gtp:4190> ;
    dv:x-iuphar <http://bio2rdf.org/iuphar:4190> ;
    dv:x-kegg <http://bio2rdf.org/kegg:D00319> ;
    dv:x-ndc <http://bio2rdf.org/ndc:0378-5011-01> ;
    dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA449591> ;
    dv:x-pubchemcompound <http://bio2rdf.org/pubchem.compound:3333> ;
    dv:x-pubchemsubstance <http://bio2rdf.org/pubchem.substance:46506968> ;
    dv:x-wikipedia <http://bio2rdf.org/wikipedia:Felodipine> ;
    dct:description "Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels. Felodipine is used to treat mild to moderate essential hypertension."@en ;
    dct:identifier "drugbank:DB01023" ;
    dct:title "Felodipine"@en ;
    a dv:Drug ;
    rdfs:label "Felodipine [drugbank:DB01023]"@en ;
    rdfs:seeAlso <http://www.drugbank.ca/drugs/DB01023> , <http://www.drugs.com/cdi/felodipine.html> , <http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileName=ple1339.html&contentName=Plendil&contentId=593> , <http://www.rxlist.com/cgi/generic2/felo.htm> .
}
sub:provenance {
   sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo <http://drugbank.ca> .
}
sub:publicationInfo {
   sub:signature.MCwCFByMXeJ69lEw npx:hasPublicKey "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" ;
    npx:hasSignature "MCwCFByMXeJ69lEw96MMpsGfsYoY/X2AAhRBm2MBg0LB4BMQIUYgxZPLMYCPAw==" ;
    npx:signedBy instance: .
  this: dct:created "2018-03-30T11:11:04.896+02:00"^^xsd:dateTime ;
    dct:license <https://creativecommons.org/licenses/by-nc/4.0/> ;
    npx:hasSignatureElement sub:signature.MCwCFByMXeJ69lEw ;
    prov:wasGeneratedBy process: .
  instance: prov:specializationOf codebase: ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
  process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475" ;
    prov:used version: ;
    prov:wasAssociatedWith instance: ;
    prov:wasStartedBy orcid:0000-0002-1267-0234 .
  version: dct:isVersionOf codebase: ;
    pav:version "eda7951a5f6c622c5d2132f50c3093138484a349" ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}