. . . . . . . . . . . . "a(CHEBI:metformin) -| bp(GOBP:gluconeogenesis)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "metformin is as an activator of the AmPK–lKb1 pathway5,126. In liver, this results in inhibition of gluconeogenesis and hepatic glucose output, which in turn reduces circulating glucose level, resulting in a secondary decrease in insulin level. In transformed epithelial cells, metformin, similarly to other AmPK activators, inhibits rather than increases insulin-stimulated proliferation6,7." . . "Selventa" . . . . "2014-07-03T14:33:29.449+02:00"^^ . . .