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p(HGNC:IL1B) -> tscript(p(HGNC:CEBPB))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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IL-1beta markedly induced the luciferase activity in the MH7A cells transfected with the luciferase reporter plasmid carrying the IL-6 promoter. The luciferase activity was significantly decreased when the region (-159 to -142bp) was deleted which includes the C/EBPbeta consensus element. A 5bp mutation introduced into the C/EBPbeta binding element reduced the induction of IL-6 promoter in response to IL-1beta to 40%.
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Selventa
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2014-07-03T14:34:06.133+02:00
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