sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "20131211" . sub:_4prov:value "To determine the capacity of EGFR inhibition to block PGE2-dependent cell proliferation, cells were pretreated with Erlotinib or PD153035 prior to PGE2 stimulation. We observed a significant increase of NSCLC cell proliferation in response to PGE2 treatment that was resistant to EGFR inhibition (Fig. 6). Treatment with EGFR inhibitors or sc58236 alone had only a modest effect on cell proliferation. However, treatment with the combination of both drugs significantly decreased proliferation of NSCLC cells compared with either drug alone or nontreated control cells." ; prov:wasQuotedFrompubmed:16024629 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:16024629 ; prov:wasDerivedFrombeldoc: , sub:_4 . }