sub:assertion {
d:DB00258 dv:ddi-interactor-in dr:DB00258_DB00451 .
d:DB00451 dv:ddi-interactor-in dr:DB00258_DB00451 .
dr:DB00258_DB00451 dcterms:identifier "drugbank_resource:DB00258_DB00451" ;
dcterms:title "DDI between Calcium Acetate and Levothyroxine - Calcium salts such as calcium acetate may diminish the therapeutic effect of thyroid products such as levothyroxine. Separate the doses of the thyroid product and the oral calcium supplement by at least 4 hours. Monitor for decreased therapeutic effects of thyroid products if an oral calcium supplement is initiated/dose increased, or increased effects if an oral calcium supplement is discontinued/dose decreased."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Calcium Acetate and Levothyroxine - Calcium salts such as calcium acetate may diminish the therapeutic effect of thyroid products such as levothyroxine. Separate the doses of the thyroid product and the oral calcium supplement by at least 4 hours. Monitor for decreased therapeutic effects of thyroid products if an oral calcium supplement is initiated/dose increased, or increased effects if an oral calcium supplement is discontinued/dose decreased. [drugbank_resource:DB00258_DB00451]"@en .
}