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[Apert syndrome, characterised by craniosynostosis, craniofacial anomalies, and symmetrical syndactyly of the digits (cutaneous and bony fusion), has been associated with two canonical mutations in the FGFR2 gene (S252W, P253R) in the great majority of cases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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