@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix chebi: . @prefix Protein: . @prefix mgi: . @prefix geneProductOf: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: mgi:1351606; a Protein: . sub:_2 occursIn: obo:UBERON_0000006, species:10090; rdf:object sub:_1; rdf:predicate belv:increases; rdf:subject chebi:44952; a rdf:Statement . sub:assertion rdfs:label "a(CHEBI:\"palmitic acid\") -> p(MGI:Sytl4)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "20131211" . sub:_3 prov:value "Granuphilin was an effector of Rab27a, and its overexpression was reported to inhibit exocytosis of insulin granules (35–37). We recently reported that granuphilin promoter was a direct target of SREBP-1c and that the SREBP-1c/granuphilin pathway was a potential mechanism for impairment GSIS in diabetes, leading to ?-cell lipotoxicity (38). This key molecule of lipotoxicity was upregulated by palmitate and suppressed by palmitate-EPA at both mRNA and protein levels (supplemental Fig. 2A; Fig. 2D)."; prov:wasQuotedFrom pubmed:18458149 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:18458149; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:33:21.141+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }