. . . . . . . . . . . . "a(CHEBI:\"palmitic acid\") -> p(MGI:Sytl4)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Granuphilin was an effector of Rab27a, and its overexpression was reported to inhibit exocytosis of insulin granules (35–37). We recently reported that granuphilin promoter was a direct target of SREBP-1c and that the SREBP-1c/granuphilin pathway was a potential mechanism for impairment GSIS in diabetes, leading to ?-cell lipotoxicity (38). This key molecule of lipotoxicity was upregulated by palmitate and suppressed by palmitate-EPA at both mRNA and protein levels (supplemental Fig. 2A; Fig. 2D)." . . "Selventa" . . . . "2014-07-03T14:33:21.141+02:00"^^ . . .