. . . . . . . . . . . . "[We developed the hypothesis that FMRP targets contribute to ASD via two distinct etiologies: (1) ultra-rare and highly penetrant single disruptions of embryonically upregulated FMRP targets ('single-hit etiology') or (2) the combination of multiple less penetrant disruptions of nonembryonic, synaptic FMRP targets ('multiple-hit etiology').]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2015-02-27"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2015-08-25T14:41:37+02:00"^^ . . . . . . . . . . . "v3.0.0.0" . "v3.0.0" .