[ { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#pubinfo" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#Head" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_1", "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0016301" ], "http://semanticscience.org/resource/SIO_000139" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_2" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_2", "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ], "http://purl.obolibrary.org/obo/RO_0002204" : [ { "@id" : "http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/PDGFR%20Family" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_3", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://purl.obolibrary.org/obo/BFO_0000066" : [ { "@id" : "http://purl.obolibrary.org/obo/CL_0000057" }, { "@id" : "http://purl.obolibrary.org/obo/UBERON_0002048" }, { "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_1" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "http://www.selventa.com/vocabulary/increases" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=5586" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#assertion", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "a(CHEBI:\"hydrogen peroxide\") -> kin(p(SFAM:\"PDGFR Family\"))" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#assertion" }, { "@graph" : [ { "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel", "http://purl.org/dc/elements/1.1/description" : [ { "@value" : "Approximately 61,000 statements." } ], "http://purl.org/dc/elements/1.1/rights" : [ { "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved." } ], "http://purl.org/dc/elements/1.1/title" : [ { "@value" : "BEL Framework Large Corpus Document" } ], "http://purl.org/pav/authoredBy" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_5" } ], "http://purl.org/pav/version" : [ { "@value" : "20131211" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_4", "http://www.w3.org/ns/prov#value" : [ { "@value" : "The relationship between NOX-mediated oxidant signaling and tyrosine phosphorylation was first indicated by pioneering studies by Finkel and Rhee and their co-workers (39,40), who demonstrated that the activation of receptor tyrosine kinases by growth factors, such as epidermal growth factor (EGF) or platelet-derived growth factor (PDGF), is associated with transient and regulated cellular production of H2O2, which amplifies tyrosine kinase signaling by temporally inactivating a protein tyrosine phosphatase (PTP)." } ], "http://www.w3.org/ns/prov#wasQuotedFrom" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/18164271" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_5", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Selventa" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#assertion", "http://www.w3.org/ns/prov#hadPrimarySource" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/18164271" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel" }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#_4" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#provenance" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2014-07-03T14:33:14.301+02:00" } ], "http://purl.org/pav/createdBy" : [ { "@id" : "http://orcid.org/0000-0001-6818-334X" }, { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAPdcW2UEXKIIuTYwlprgUVlotqAtfihbvhOkzKtqRaTo#pubinfo" } ]