@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix go: .
@prefix Protein: .
@prefix pfh: .
@prefix geneProductOf: .
@prefix hasAgent: .
@prefix hgnc: .
@prefix proteinModification: .
@prefix psimod: .
@prefix mesh: .
@prefix occursIn: .
@prefix species: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 hasAgent: sub:_2;
a go:0016301 .
sub:_2 geneProductOf: pfh:MAPK%20Erk1%2F3%20Family;
a Protein: .
sub:_3 belv:variantOf hgnc:11364;
a proteinModification:, psimod:00696 .
sub:_4 occursIn: mesh:D009101, species:9606;
rdf:object sub:_3;
rdf:predicate belv:increases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "kin(p(PFH:\"MAPK Erk1/3 Family\")) -> p(HGNC:STAT3,pmod(P,S,727))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_6;
pav:version "1.4" .
sub:_5 prov:value "enhanced proliferation of KMS-11. bFGF but not IL-6 stimu- lation induces the phosphorylation of Ser727 in STAT3, and a selective MEK1/2 inhibitor abolishes the serine- but not tyrosine-phosphorylation of STAT3 in response to bFGF and IL-6 stimulations, supportingthe notion that two independent signaling pathways converge on STAT3 to regulate its func- tion in the cell. Thus, the bFGF-induced activation of ERK1/ 2 pathway is involved in the phosphorylation of the critical serine residue of STAT3 ";
prov:wasQuotedFrom pubmed:17142955 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:17142955;
prov:wasDerivedFrom beldoc:, sub:_5 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:30:48.488+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}