. . . . . . . . . . . . . . . . . . . . . . "composite(p(HGNC:CD28),complex(p(SCOMP:\"T Cell Receptor Complex\"))) -> kin(p(SFAM:\"AKT Family\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "he CD28 signaling pathway primarily involves a small subset of signaling molecules that are also implicated in TCR signal transmission, in particular the phosphoinositide-3 kinase (PI3-K) pathway with downstream activation of AKT [32,33], and activation of TEC protein kinases and of interleukin-2-inducible T-cell kinases [27,34]. AKT activation cooperates with the TCR-induced activation of protein kinase C (PKC)? to activate the NF-?B pathway, which is otherwise only slightly activated by TCR alone. " . . "Selventa" . . . . "2014-07-03T14:33:27.993+02:00"^^ . . .