@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .
dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_head {
  this: np:hasAssertion dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_assertion ;
    np:hasProvenance dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_provenance ;
    np:hasPublicationInfo dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_publicationInfo ;
    a np:Nanopublication .
  dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_assertion a np:Assertion .
  dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_provenance a np:Provenance .
  dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_publicationInfo a np:PublicationInfo .
}
dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_assertion {
  miriam-gene:9516 a ncit:C16612 .
  lld:C1306459 a ncit:C7057 .
  dgn-gda:DGNc4d4a0bf51f856c846f3941f1f3e538f sio:SIO_000628 miriam-gene:9516 , lld:C1306459 ;
    a sio:SIO_001121 .
}
dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_provenance {
  dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_assertion dcterms:description "[Simple gene dosage changes are difficult however, to incorporate into this model, in part due to negative feedback loops that govern major cancer mutational targets (e.g., TP53, PTCH, SMAD4) and essentially preclude a haploinsufficient phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_literature ;
    sio:SIO_000772 miriam-pubmed:16721048 ;
    prov:wasDerivedFrom dgn-void:befree-20150227 ;
    prov:wasGeneratedBy eco:ECO_0000203 .
  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  dgn-void:source_evidence_literature a eco:ECO_0000212 ;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en ;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}
dgn-np:NP825103.RAPDULj-fvSplhggkB4mLBjDiB7FGdJFe3Ul50m2Rn7gY130_publicationInfo {
  this: dcterms:created "2015-08-25T14:46:00+02:00"^^xsd:dateTime ;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/> ;
    dcterms:rightsHolder dgn-void:IBIGroup ;
    dcterms:subject sio:SIO_000983 ;
    prv:usedData dgn-void:disgenetv3.0rdf ;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269> , <http://orcid.org/0000-0002-7534-7661> , <http://orcid.org/0000-0002-9383-528X> , <http://orcid.org/0000-0003-0169-8159> , <http://orcid.org/0000-0003-1244-7654> ;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159> ;
    pav:version "v3.0.0.0" .
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}