<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE> <http://www.nanopub.org/nschema#hasAssertion> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#head> .
<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE> <http://www.nanopub.org/nschema#hasProvenance> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#head> .
<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE> <http://www.nanopub.org/nschema#hasPublicationInfo> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#publicationInfo> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#head> .
<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.nanopub.org/nschema#Nanopublication> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#head> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/bio2rdf_vocabulary:identifier> "DB00543" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/bio2rdf_vocabulary:namespace> "drugbank" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/bio2rdf_vocabulary:uri> "http://bio2rdf.org/drugbank:DB00543" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/bio2rdf_vocabulary:x-identifiers.org> <http://identifiers.org/drugbank/DB00543> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:drugbank-id> "APRD00142" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:drugbank-id> "DB00543" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-atc> <http://bio2rdf.org/atc:N06AA17> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-bindingdb> <http://bio2rdf.org/bindingdb:22870> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-cas> <http://bio2rdf.org/cas:14028-44-5> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-chebi> <http://bio2rdf.org/chebi:2675> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-chemspider> <http://bio2rdf.org/chemspider:2085> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-dpd> <http://bio2rdf.org/dpd:527106> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-gtp> <http://bio2rdf.org/gtp:201> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-iuphar> <http://bio2rdf.org/iuphar:201> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-kegg> <http://bio2rdf.org/kegg:D00228> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-ndc> <http://bio2rdf.org/ndc:0591-5713-01> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-pharmgkb> <http://bio2rdf.org/pharmgkb:PA448405> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-pubchemcompound> <http://bio2rdf.org/pubchem.compound:2170> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-pubchemsubstance> <http://bio2rdf.org/pubchem.substance:46509117> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://bio2rdf.org/drugbank_vocabulary:x-wikipedia> <http://bio2rdf.org/wikipedia:Amoxapine> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://purl.org/dc/terms/description> "Amoxapine, the <i>N</i>-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation. In depressed individuals, amoxapine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. In addition, TCAs down-regulate cerebral cortical &beta;-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Amoxapine may be used to treat neurotic and reactive depressive disorders, endogenous and psychotic depression, and mixed symptoms of depression and anxiety or agitation."@en <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://purl.org/dc/terms/identifier> "drugbank:DB00543" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://purl.org/dc/terms/title> "Amoxapine"@en <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://bio2rdf.org/drugbank_vocabulary:Drug> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://www.w3.org/2000/01/rdf-schema#label> "Amoxapine [drugbank:DB00543]"@en <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <http://www.drugbank.ca/drugs/DB00543> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <http://www.drugs.com/cdi/amoxapine.html> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <http://www.rxlist.com/cgi/generic/amoxapine.htm> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> .
<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#assertion> <http://www.w3.org/ns/prov#wasDerivedFrom> <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
<http://bio2rdf.org/drugbank_resource:bio2rdf.dataset.drugbank.R3> <http://www.w3.org/ns/dcat#distribution> <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
<http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> <http://purl.org/dc/terms/created> "2015-01-09T17:00:50-05:00"^^<http://www.w3.org/2001/XMLSchema#dateTime> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
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<http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> <http://purl.org/pav/retrievedOn> "2014-11-12T07:57:03-05:00"^^<http://www.w3.org/2001/XMLSchema#dateTime> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
<http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> <http://www.w3.org/ns/prov#wasDerivedFrom> <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
<http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> <http://www.w3.org/ns/prov#wasAttributedTo> <http://drugbank.ca> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#provenance> .
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<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#signature.MC0CFCGHr5FF3CUo> <http://purl.org/nanopub/x/signedBy> <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#publicationInfo> .
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<http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE> <http://www.w3.org/ns/prov#wasGeneratedBy> <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#publicationInfo> .
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<https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> <http://purl.org/pav/version> "eda7951a5f6c622c5d2132f50c3093138484a349" <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#publicationInfo> .
<https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> <http://www.w3.org/ns/prov#wasAttributedTo> <http://orcid.org/0000-0002-1267-0234> <http://bio2rdf.org/drugbank:DB00543_nanopub.RAPCnYAb-8PjiHaYT9BSi-6YPGFIk4XwQlazZCAZFUfnE#publicationInfo> .