sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "20131211" .
  sub:_4 prov:value "At 4 weeks of age, in the fed state, Ncb5or -/- mice had normal blood glucose levels (Fig. 2a) but insulin levels were 40% those of wild-type littermates (Fig. 2b). These animals had impaired tolerance to an i.p. injection of glucose (Fig. 2c), suggesting decreased insulin reserve, i.e., prediabetes. By 7 weeks of age, the blood glucose levels in Ncb5or -/- mice were 3-fold higher than those in +/+ mice during the fed state or after an overnight fast (Fig. 2a). The hyperglycemia in the Ncb5or -/- animals was associated with a marked reduction in plasma insulin. In the fed state, insulin levels of 7-week-old Ncb5or -/- animals were decreased to 25% of the levels in normal animals (Fig. 2b). Insulin was barely detectable in the plasma of fasting Ncb5or -/- animals (data not shown). These data indicate that, between 4 and 7 weeks of age, there was a progressive deterioration of glucose homeostasis in Ncb5or -/- mice." ;
    prov:wasQuotedFrom pubmed:15247412 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:15247412 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}