@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAP07HL_X5GoBwJyxtwNl1s51qgt6P9RVKOVXDvn_H0GQ> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAP07HL_X5GoBwJyxtwNl1s51qgt6P9RVKOVXDvn_H0GQ#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix pfh: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-protein-families/> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 hasAgent: sub:_2 ;
    a go:0042789 .
  sub:_2 geneProductOf: pfh:NOTCH%20Family ;
    a Protein: .
  sub:_3 hasAgent: sub:_4 ;
    a go:0003824 .
  sub:_4 geneProductOf: hgnc:10848 ;
    a Protein: .
  sub:_5 occursIn: mesh:D012867 , species:9606 ;
    rdf:object sub:_3 ;
    rdf:predicate belv:decreases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "tscript(p(PFH:\"NOTCH Family\")) -| cat(p(HGNC:SHH))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "1.4" .
  sub:_6 prov:value "Notch1 exerts its tumour-suppressive effect in the mouse skin partially by repressing components of the Wnt (see a) and Shh (see b) signalling pathways.Activation of both pathways has been associated with many forms of cancer.Activation of WNT signalling has been linked with colorectal cancer, hepatocellular tumours, pilomatricomas, melanomas and other types of cancer (for a review, see REF. 98).Aberrant SHH signalling has been associated with sporadic basal-cell carcinoma, medulloblastoma and rhabdomyosarcoma (for a review, see REF. 138)." ;
    prov:wasQuotedFrom pubmed:14570040 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:14570040 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:30:17.556+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}