@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_head {
  this: np:hasAssertion dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_assertion;
    np:hasProvenance dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_provenance;
    np:hasPublicationInfo dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_assertion a np:Assertion .
  
  dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_provenance a np:Provenance .
  
  dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_assertion {
  miriam-gene:3651 a ncit:C16612 .
  
  lld:C0020456 a ncit:C7057 .
  
  dgn-gda:DGNa2ec9a024f03a2833de44e41360eab66 sio:SIO_000628 miriam-gene:3651, lld:C0020456;
    a sio:SIO_001121 .
}

dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_provenance {
  dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_assertion dcterms:description
      "[At the same time points, high hyperglycemia rats showed a global alteration in gene expression with decreased mRNA for insulin, IAPP, islet-associated transcription factors (pancreatic and duodenal homeobox-1, BETA2/NeuroD, Nkx6.1, and hepatocyte nuclear factor 1 alpha), beta-cell metabolic enzymes (glucose transporter 2, glucokinase, mitochondrial glycerol phosphate dehydrogenase, and pyruvate carboxylase), and ion channels/pumps (Kir6.2, VDCC beta, and sarcoplasmic reticulum Ca(2+)-ATPase 3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_predicted;
    sio:SIO_000772 miriam-pubmed:12438314;
    prov:wasDerivedFrom dgn-void:rgd-20150221;
    prov:wasGeneratedBy eco:ECO_0000218 .
  
  dgn-void:rgd-20150221 pav:importedOn "2015-02-21"^^xsd:date .
  
  dgn-void:source_evidence_predicted a eco:ECO_0000266;
    rdfs:comment "Gene-disease associations inferred from animal model manually asserted gene-disease associations."@en;
    rdfs:label "DisGeNET evidence - PREDICTED"@en .
}

dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_publicationInfo {
  this: dcterms:created "2015-08-25T14:38:05+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}