dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_provenance {
dgn-np:NP46198.RAOwTVEyesez_FTkjXNcI2L03u5QNQOwUR4AaRL20x3d0130_assertion dcterms:description "[At the same time points, high hyperglycemia rats showed a global alteration in gene expression with decreased mRNA for insulin, IAPP, islet-associated transcription factors (pancreatic and duodenal homeobox-1, BETA2/NeuroD, Nkx6.1, and hepatocyte nuclear factor 1 alpha), beta-cell metabolic enzymes (glucose transporter 2, glucokinase, mitochondrial glycerol phosphate dehydrogenase, and pyruvate carboxylase), and ion channels/pumps (Kir6.2, VDCC beta, and sarcoplasmic reticulum Ca(2+)-ATPase 3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
wi:evidence dgn-void:source_evidence_predicted ;
sio:SIO_000772 miriam-pubmed:12438314 ;
prov:wasDerivedFrom dgn-void:rgd-20150221 ;
prov:wasGeneratedBy eco:ECO_0000218 .
dgn-void:rgd-20150221 pav:importedOn "2015-02-21"^^
xsd:date .
dgn-void:source_evidence_predicted a eco:ECO_0000266 ;
rdfs:comment "Gene-disease associations inferred from animal model manually asserted gene-disease associations."@en ;
rdfs:label "DisGeNET evidence - PREDICTED"@en .
}