@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix obo: .
@prefix occursIn: .
@prefix species: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 geneProductOf: hgnc:10672;
a Protein: .
sub:_2 geneProductOf: hgnc:905;
a Protein: .
sub:_3 occursIn: obo:CLO_0007043, species:9606;
rdf:object sub:_2;
rdf:predicate belv:increases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "p(HGNC:CXCL12) -> p(HGNC:AXL)" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_5;
pav:version "20131211" .
sub:_4 prov:value "ranscriptional response of selected cellular genes in Jurkat T cells upon SDF-1 exposure. Among the genes which showed a continuous increase in their expression following SDF-1 exposure were those involved in detoxification, DNA repair, apoptosis, TCR signal transduction, cytokinesis, cell adhesion molecules, chemokine receptors, and IFN-related molecules. The effects of MEK and PI3K inhibitors (50 µM PD098059 (20 21 ) and 20 µM LY294002 (22 ), respectively) on the expression of these genes are also shown. Jurkat cells were exposed to SDF-1 in the presence of the inhibitors for 6 h without FCS. Reference mRNA was obtained from cells exposed to the inhibitors but not to SDF-1. The expression ratios were determined as described in the legend to Fig. 1. ";
prov:wasQuotedFrom pubmed:11544290 .
sub:_5 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:11544290;
prov:wasDerivedFrom beldoc:, sub:_4 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:31:43.410+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}